We have receptors for cannabinoids in the whole body, but the first type (CB1) are very dense in the pain pathways of the brain, spine, and nerves. The second type (CB2) are more important for the immune system but is also involved in inflammation. By gently acting on both pathways, our internal cannabinoids and CBD can balance both pain and inflammation [64].
          When you know bodybuilding, you may be familiar with anabolic and anti-catabolic supplements. For bodybuilding, coaches recommend anti-catabolic supplements because they reduce the production of catabolic hormones, which contribute to muscle loss. By comparison, anabolic supplements increase the production of anabolic hormones, which stimulate protein synthesis for faster muscle growth. When the CBD adheres to your body's receptors, CBD offers benefits that make it an asset for bodybuilding.
Putting this in perspective, eating a portion of grapefruit would have a similar effect on the aforementioned liver enzymes. So neutralizing P450 enzymes should be viewed as a minor side effect of cannabidiol. However, if you are taking pharmaceutical drugs and wish to take CBD, you should discuss any potential complications regarding reduced P450 enzyme activity with your doctor and/or pharmacist.
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