Great points and thanks for the clarification. To be clear, THC products are not readily available to purchase online (legally), so anyone hoping to try the CBD oil trend will have to settle for these alternatives for the time being, until the FDA approves more variations. Many people who are new to CBD see these options as a good entry-point before they experiment with larger mg amounts, and the reviews online are strong. Still, you are correct that full spectrum CBD oils may ultimately be better once they are legally approved to sell online to everyone.
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In a small study published in the journal JCI Insight in 2017, researchers observed that CBD may help prevent stress-related changes in blood pressure. For the study, nine healthy male volunteers took a single dose of either CBD or placebo. Compared to those given the placebo, those treated with CBD had lower blood pressure both before and after experiencing a stressful event.
Another study (performed in 2011) found a link between nervous and immune system involvement and IBS. When CBD was used to treat IBS patients, regulation of gliosis in the nervous system (commonly associated with negative IBS effects) seemed possible, without the psychoactive and other common effects of traditional treatments or even medical marijuana. (43)
Putting this in perspective, eating a portion of grapefruit would have a similar effect on the aforementioned liver enzymes. So neutralizing P450 enzymes should be viewed as a minor side effect of cannabidiol. However, if you are taking pharmaceutical drugs and wish to take CBD, you should discuss any potential complications regarding reduced P450 enzyme activity with your doctor and/or pharmacist.
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